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Cat. No.: HY-118420

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BMS-185411

BMS-185411 is a selective retinoic acid receptor alpha (RARα) antagonist, with an IC₅₀ value of 140 nM.

For research use only. We do not sell to patients.

CAS No.: 166977-24-8
Formula: C₂₆H₂₃NO₃
Molecular Weight:397.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BMS-185411 Chemical Structure

CAS No.: 166977-24-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BMS-185411 is a selective retinoic acid receptor alpha (RARα) antagonist, with an IC₅₀ value of 140 nM^[1].

All RAR/RXR Isoforms :

Chemical Information

CAS No. 166977-24-8
Molecular Weight 397.47
Formula C₂₆H₂₃NO₃
SMILES

O=C(O)C1=CC=C(NC(C2=CC=C3C(C)(C)CC=C(C4=CC=CC=C4)C3=C2)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Md Abdullah Al Noman, et al. Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception. Eur J Med Chem. 2023 Dec 5:261:115821. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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References

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BMS-185411

All RAR/RXR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BMS-185411 Related Classifications

HY-118420 Related Classifications