Izencitinib (Standard)
Izencitinib (Standard) is the analytical standard of Izencitinib (HY-109148). This product is intended for research and analytical applications. Izencitinib (TD-1473) is an orally active, non-selective and gut-restricted JAK inhibitor. Izencitinib (TD-1473) can be used in the study for ulcerative colitis.
For research use only. We do not sell to patients.
- CAS No.: 2051918-33-1
- Formula: C22H26N8
- Molecular Weight:402.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2051918-33-1
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Molecular Weight 402.50
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Formula C22H26N8
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SMILES
CC1=CC(NC2=CC3=C(C=CC=N3)C(N[C@@H]4C[C@@H](CC5)N(CCC#N)[C@@H]5C4)=N2)=NN1
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Synonyms
TD-1473 (Standard); JNJ-8398 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kevin S Currie, et al. Small-molecule agents for the treatment of inflammatory bowel disease. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2034-2041. [Content Brief]
[2]. William J Sandborn, et al. Development of Gut-Selective Pan-Janus Kinase Inhibitor TD-1473 for Ulcerative Colitis: A Translational Medicine Programme. J Crohns Colitis. 2020 Sep 16;14(9):1202-1213. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)