PfFAS-II inhibitor 1
PfFAS-II inhibitor 1 (Compound 3) is a Plasmodium falciparum type II fatty acid biosynthesis pathway (PfFAS-II) inhibitor, with an IC50 of 0.63 μM for PfFabI enzyme. PfFAS-II inhibitor 1 has antimalarial activity.
For research use only. We do not sell to patients.
- CAS No.: 1459704-68-7
- Formula: C15H9ClO4
- Molecular Weight:288.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Plasmodium falciparum Type II Fatty Acid Biosynthesis Pathway (PfFAS-II)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L6 | IC50 |
96.2 μM
Compound: 3
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Cytotoxicity against rat L6 cells assessed as growth inhibition after 72 hrs by fluorometric analysis
Cytotoxicity against rat L6 cells assessed as growth inhibition after 72 hrs by fluorometric analysis
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[PMID: 24063369] |
Chemical Information
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CAS No. 1459704-68-7
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Molecular Weight 288.68
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Formula C15H9ClO4
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SMILES
O=C1OC2=C(C=C1)C=C(OC3=CC=C(C=C3O)Cl)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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