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Cat. No.: HY-W747797

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Cinobufagine-d₃

Cinobufagine-d₃ is the deuterium labeled Cinobufagin (HY-N0421). Cinobufagin is an anticancer agent that can be secreted by the Asiatic toad Bufo gargarizans. Cinobufagin induces the cell cycle arrests in the G1 phase or G2/M phase, leading to apoptosis in cancer cells. Cinobufagin inhibits tumor growth in melanoma and glioblastoma multiforme xenograft mouse models.

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Formule: C₂₆H₃₁D₃O₆
Masse moléculaire:445.56

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (245 KB)

Cinobufagine-d₃ Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- Application
Chemical Information
Pureté et documentation
Calculators
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Activité biologique

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 470-37-1
Masse moléculaire 445.56
Formule C₂₆H₃₁D₃O₆
SMILES

O[C@H]1CC[C@]2([C@@]([H])(C1)CC[C@@]3([C@@]2(CC[C@]4([C@@]35O[C@@H]5[C@@H]([C@@H]4C(C=C6)=COC6=O)OC(C([2H])([2H])[2H])=O)C)[H])[H])C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.