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Cat. No.: HY-175173

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EGFR-IN-166

EGFR-IN-166 (Compound 2) is a EGFR inhibitor. EGFR-IN-166 has potent anticancer activity against breast cancer cells with IC₅₀s of 69.63 and 22.84 μM for MCF-7 and MDA-MB-231 cells, respectively. EGFR-IN-166 significantly inhibits cell migration and EGFR expression. EGFR-IN-166 can be used for breast cancer research.

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CAS No.: 503443-98-9
Formule: C₁₉H₁₅N₃O₂S
Masse moléculaire:349.41

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

EGFR-IN-166 Chemical Structure

CAS No.: 503443-98-9

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Activité biologique

Description

Voir tous les produits spécifiques à Isoform EGFR :

Chemical Information

CAS No. 503443-98-9
Masse moléculaire 349.41
Formule C₁₉H₁₅N₃O₂S
SMILES

O=C1CN(C2=CC=CC=C2)/C(S1)=C3C(C)=NN(C4=CC=CC=C4)C/3=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mahmoud SE, et al. Discovery and molecular characterization of a potent thiazolyl-pyrazole hybrid targeting EGFR for breast cancer therapy. Sci Rep. 2025 Jul 3;15(1):23743. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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EGFR-IN-166

Voir tous les produits spécifiques à Isoform EGFR