Hancockiamide D
Hancockiamide D is a phenylpropanoid piperazine alkaloid found in the Australian soil fungus Aspergillus hancockii. Hancockiamide D induces cytotoxic activity in cancer cells and shows no activity in fibroblasts. Hancockiamide D can be used for the research of murine myeloma.
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- CAS No.: 2758265-37-9
- Formule: C20H26N2O3
- Masse moléculaire:342.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Hancockiamide D (compound 4) undergoes N-trans-cinnamoylation catalyzed by the single-module nonribosomal peptide synthetase Hkm11 in vitro to produce Hancockiamide A; the cytochrome P450 Hkm5 converts a portion of Hancockiamide D into H[1].
Hancockiamide D exhibits potent cytotoxic activity against mouse myeloma NS-1 cells (MIC = 3.1 μg/mL), while showing no activity against neonatal foreskin fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2758265-37-9
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Masse moléculaire 342.44
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Formule C20H26N2O3
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SMILES
C(C1=CC(OC)=C(O)C(OC)=C1)[C@H]2CN[C@@H](CC3=CC=CC=C3)CN2
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Structure Classification
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Initial Source
Aspergillus hancockii
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hancockiamide D Related Classifications
HY-N19181 Related Classifications
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