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Cat. No.: HY-109116

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Hydromethylthionine

(Synonyms: Leukomethylene blue)

6 Cited Publications

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Based on 6 publication(s) in Google Scholar

Hydromethylthionine (Leukomethylene blue) has a very active photochemically active reagent, especially in its interaction with dissolved oxygen. The photochemical activity of Hydromethylthionine is mainly regulated by the reaction of its triplet state with dissolved oxygen, which reacts with dissolved oxygen to form Methylene Blue (HY-14536) and hydronium ions under ultraviolet light. Hydromethylthionine can be used for the photodegradation of model pollutants in semiconductor photocatalysis and for the study of indicators in chemical analysis.

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CAS No.: 613-11-6
Formule: C₁₆H₁₉N₃S
Masse moléculaire:285.41

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-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Hydromethylthionine Chemical Structure

CAS No.: 613-11-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Essai clinique
Chemical Information
Publications (6)
Pureté et documentation
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Activité biologique

Description

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 613-11-6
Appearance Solid
Masse moléculaire 285.41
Formule C₁₆H₁₉N₃S
Color Brown to black
SMILES

CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1
Synonyms

Leukomethylene blue
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (6)

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Nat Commun

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology. [Abstract]

2023 Sep 6;14(1):5444. PMID: 37673952
Adv Sci (Weinh)

Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis. [Abstract]

2024 Jun;11(23):e2310134. PMID: 38634567
Cancers (Basel)

Targeting Microtubule-Associated Protein Tau in Chemotherapy-Resistant Models of High-Grade Serous Ovarian Carcinoma. [Abstract]

2022 Sep 19;14(18):4535. PMID: 36139693
Bioorg Med Chem

Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation. [Abstract]

2018 Sep 1;26(16):4693-4705. PMID: 30107970

Hydromethylthionine purchased from MedChemExpress. Usage Cited in: Bioorg Med Chem. 2018 Sep 1;26(16):4693-4705. [Abstract]

Imaging of HEK-293T cells incubated with or without LMTM (0.5 μM) and 30 (1 μM).
Research Square Print

August 19th, 2022.
Research Square Preprint

2020 Dec.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lee S K, et al. Novel photochemistry of leuco-Methylene Blue[J]. Chemical Communications, 2003 (18): 2366-2367. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Hydromethylthionine

6 Cited Publications

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Publications (6)
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Hydromethylthionine purchased from MedChemExpress. Usage Cited in: Bioorg Med Chem. 2018 Sep 1;26(16):4693-4705. [Abstract]

Customer Validation
Imaging of HEK-293T cells incubated with or without LMTM (0.5 μM) and 30 (1 μM).

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Hydromethylthionine

Publications Citing Use of MedChemExpress (MCE) Hydromethylthionine

Activité biologique

Chemical Information

Publications (6)

Pureté et documentation

Références

Calculators

Help & FAQs

Hydromethylthionine Related Classifications

HY-109116 Related Classifications