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Cat. No.: HY-109116A

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Hydromethylthionine dihydrobromide

(Synonyms: Leukomethylene blue dihydrobromide; LMTM dihydrobromide)

Hydromethylthionine dihydrobromide (Leukomethylene blue dihydrobromide) is a potent inhibitor of TAU protein aggregation. Hydromethylthionine dihydrobromide reduces neurodegeneration by interacting with TAU proteins and preventing them from forming neurotoxic aggregates. Hydromethylthionine dihydrobromide can be used in the study of Alzheimer's disease and other TAU related disorders.

For research use only. We do not sell to patients.

CAS No.: 951131-15-0
Formula: C₁₆H₂₁Br₂N₃S
Molecular Weight:447.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Hydromethylthionine dihydrobromide Chemical Structure

CAS No.: 951131-15-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 951131-15-0
Molecular Weight 447.23
Formula C₁₆H₂₁Br₂N₃S
SMILES

CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1.Br.Br
Synonyms

Leukomethylene blue dihydrobromide; LMTM dihydrobromide
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kondak C, et al. Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine[J]. Journal of neurochemistry, 2022, 160(2): 172-184. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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