Hydromethylthionine
Based on 6 publication(s) in Google Scholar
Hydromethylthionine (Leukomethylene blue) has a very active photochemically active reagent, especially in its interaction with dissolved oxygen. The photochemical activity of Hydromethylthionine is mainly regulated by the reaction of its triplet state with dissolved oxygen, which reacts with dissolved oxygen to form Methylene Blue (HY-14536) and hydronium ions under ultraviolet light. Hydromethylthionine can be used for the photodegradation of model pollutants in semiconductor photocatalysis and for the study of indicators in chemical analysis.
For research use only. We do not sell to patients.
- CAS No.: 613-11-6
- Formula: C16H19N3S
- Molecular Weight:285.41
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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- References
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Publications Citing Use of MedChemExpress (MCE) Hydromethylthionine
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IF
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 613-11-6
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Appearance Solid
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Molecular Weight 285.41
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Formula C16H19N3S
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Color Brown to black
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SMILES
CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1
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Synonyms
Leukomethylene blue
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (6)
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Journal Impact Factor
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Most Recent
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Nat Commun
Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology. [Abstract]2023 Sep 6;14(1):5444. PMID: 37673952 -
Adv Sci (Weinh)
Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis. [Abstract]2024 Jun;11(23):e2310134. PMID: 38634567 -
Cancers (Basel)
Targeting Microtubule-Associated Protein Tau in Chemotherapy-Resistant Models of High-Grade Serous Ovarian Carcinoma. [Abstract]2022 Sep 19;14(18):4535. PMID: 36139693 -
Bioorg Med Chem
Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation. [Abstract]2018 Sep 1;26(16):4693-4705. PMID: 30107970
Hydromethylthionine purchased from MedChemExpress. Usage Cited in: Bioorg Med Chem. 2018 Sep 1;26(16):4693-4705. [Abstract]
Imaging of HEK-293T cells incubated with or without LMTM (0.5 μM) and 30 (1 μM).
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Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydromethylthionine Related Classifications
HY-109116 Related Classifications
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