Merulinic acid
Merulinic acid (Geranicardic acid) is an acetylcholinesterase (AChE) inhibitor with an IC50 >94 μM against electric eel-derived AChE. Merulinic acid can be used for the research of alzheimer’s disease.
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- CAS No.: 69506-63-4
- Formule: C24H38O3
- Masse moléculaire:374.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Help & FAQs
Activité biologique
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electric eel AChE >94 μM (IC50) |
Merulinic acid (8-94 μM; 5 min) inhibits the activity of purified AChE from Electrophorus electricus by a maximum of 40%, with an IC50 value >94 μM[1].
Merulinic acid (20-213 μM; 10 min) induces conformational changes in purified AChE from Electrophorus electricus, decreasing the intrinsic tryptophan fluorescence F/F0 ratio by approximately 80% at concentrations up to 213 μM, without shifting the fluorescence emission maximum[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 69506-63-4
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Masse moléculaire 374.56
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Formule C24H38O3
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SMILES
CCCCCCCC/C=C\CCCCCCCC1=C(C(O)=CC=C1)C(O)=O
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Synonyms
Geranicardic acid
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Structure Classification
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Initial Source
Merulius tremellosus
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Merulinic acid Related Classifications
HY-N19855 Related Classifications
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