NAE-IN-3
NAE-IN-3 (compound 1) is a potent, selective and non-covalent competitive NEDD8-activating enzyme (NAE) inhibitor (IC50 = 0.8 μM). NAE-IN-3 inhibits NAE by blocking the ATP-binding domain. NAE-IN-3 exhibits selectivity over analogous E1 enzymes UAE and SAE. NAE-IN-3 can be used for cancer research.
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- CAS No.: 951950-33-7
- Formule: C17H18N4O6
- Masse moléculaire:374.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 951950-33-7
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Masse moléculaire 374.35
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Formule C17H18N4O6
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SMILES
O=C(CNC(CNC(COC1=CC2=C(N=C3N(CCC3)C2=O)C=C1)=O)=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NAE-IN-3 Related Classifications
HY-177936 Related Classifications
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