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Cat. No.: HY-144220

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NLRP3/AIM2-IN-1

NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an IC 50 value of 3.136 ± 0.7667 μ M.

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CAS No.: 3033386-91-0
Formule: C₁₅H₁₆BNO₄
Masse moléculaire:285.10

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

NLRP3/AIM2-IN-1 Chemical Structure

CAS No.: 3033386-91-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an IC 50 value of 3.136 ± 0.7667 μ M.

IC₅₀ & Target

inhibitory activity against NLRP3 and AIM2

3.136±0.76 μM (IC₅₀)

Voir tous les produits spécifiques à Isoform NOD-like Receptor (NLR) :

Chemical Information

CAS No. 3033386-91-0
Masse moléculaire 285.10
Formule C₁₅H₁₆BNO₄
SMILES

COC1=CC=C(C=C1)CC(NC2=CC=CC(B(O)O)=C2)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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NLRP3/AIM2-IN-1

Voir tous les produits spécifiques à Isoform NOD-like Receptor (NLR)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

NLRP3/AIM2-IN-1 Related Classifications

HY-144220 Related Classifications