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Cat. No.: HY-15042A

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(Rac)-MK 0686

(Rac)-MK 0686 is the racemate of MK 0686. MK 0686 is a bradykinin B₁ receptor antagonist.

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CAS No.: 1159193-97-1
Formule: C₂₂H₁₉ClF₄N₂O₄
Masse moléculaire:486.84

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(Rac)-MK 0686 Chemical Structure

CAS No.: 1159193-97-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

(Rac)-MK 0686 is the racemate of MK 0686. MK 0686 is a bradykinin B₁ receptor antagonist^[1].

IC₅₀ & Target^[1]

Bradykinin B1 Receptor (B1R)

Voir tous les produits spécifiques à Isoform Bradykinin Receptor :

Chemical Information

CAS No. 1159193-97-1
Masse moléculaire 486.84
Formule C₂₂H₁₉ClF₄N₂O₄
SMILES

O=C(C1=C(C2=CC=C(C(C)NC(C3(CC3)NC(C(F)(F)F)=O)=O)C(F)=C2)C=CC=C1Cl)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tang C, et al. CYP2C75-Involved Autoinduction of Metabolism in Rhesus Monkeys of Methyl 3-Chloro-3′-fluoro-4′-{(1 R)-1-[({1-[(trifluoroacetyl) amino] cyclopropyl} carbonyl) amino] ethyl}-1, 1′-biphenyl-2-carboxylate (MK-0686), a Bradykinin B1 Receptor Antagonist[J]. The Journal of pharmacology and experimental therapeutics, 2008, 325(3): 935-946.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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(Rac)-MK 0686

Voir tous les produits spécifiques à Isoform Bradykinin Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(Rac)-MK 0686 Related Classifications

HY-15042A Related Classifications