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Cat. No.: HY-134248

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Tubercidin 5'-triphosphate

(Synonyms: 7-Deazaadenosine 5'-triphosphate)

Tubercidin 5'-triphosphate (7-Deazaadenosine 5'-triphosphate) (Compound II) is an ATP (HY-B2176) analogue. Tubercidin 5'-triphosphate is hydrolyzable by Myosin B. Tubercidin 5'-triphosphate induces weak contraction of rabbit psoas myofibrils.

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CAS No.: 10058-66-9
Formule: C₁₁H₁₇N₄O₁₃P₃
Masse moléculaire:506.19

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Tubercidin 5'-triphosphate Chemical Structure

CAS No.: 10058-66-9

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In Vitro

Tubercidin 5'-triphosphate (0.15 mM) can be hydrolyzed by rabbit skeletal muscle myosin B under conditions of high ionic strength with Ca²⁺ (0.6 M KCl, 7 mM CaCl₂, pH 7.0, 20°C), and its hydrolysis rate is 49% of that of ATP^[1].
Tubercidin 5'-triphosphate (0.15 mM) can be hydrolyzed by rabbit skeletal muscle myosin B under conditions of low ionic strength with Mg²⁺present (0.075 M KCl, 2 mM MgCl₂, pH 7.0, 20°C), and its hydrolysis rate reaches 270% of that of ATP^[1].
Tubercidin 5'-triphosphate (0.1 mM) induces weak contraction of rabbit psoas myofibrils under the conditions of 0.04 M K⁺Cl⁻, 2 mM MgCl₂, pH 7.0 and 23°C, which is evidenced by the formation of subtle contraction bands^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 10058-66-9
Masse moléculaire 506.19
Formule C₁₁H₁₇N₄O₁₃P₃
SMILES

O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O[C@H]1N2C3=NC=NC(N)=C3C=C2
Synonyms

7-Deazaadenosine 5'-triphosphate
Livraison

Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Tonomura Y, et al. Interaction between synthetic ATP analogues and actomyosin systems. IV. J Biochem. 1967 Apr;61(4):460-72. [Content Brief]

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Tubercidin 5'-triphosphate

Voir tous les produits spécifiques à Isoform Myosin

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