COTC
COTC is a bacterial metabolite with anticancer activity that is found in S. griseosporeus. COTC inhibits glyoxalase in the presence of glutathione (GSH). COTC also inhibits the proliferation of HeLa cells (IC50 = 18 µg/mL), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.
For research use only. We do not sell to patients.
- CAS No.: 57449-30-6
- Formula: C11H14O6
- Molecular Weight:242.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 57449-30-6
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Molecular Weight 242.23
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Formula C11H14O6
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SMILES
C/C=C/C(OCC1=C[C@@H](O)[C@@H](O)[C@@H](O)C1=O)=O
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Structure Classification
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Initial Source
Streptomyces griseosporeus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)