57449-30-6
57449-30-6
Chemical Structure
COTC
- CAS No.: 57449-30-6
- Formula:C11H14O6
- Molecular Weight:242.23
InChIKey: PSJQCAMBOYBQEU-KHSNLZPESA-N
SMILES: C/C=C/C(OCC1=C[C@@H](O)[C@@H](O)[C@@H](O)C1=O)=O
Biological Activity: COTC is a bacterial metabolite with anticancer activity that is found in S. griseosporeus. COTC inhibits glyoxalase in the presence of glutathione (GSH). COTC also inhibits the proliferation of HeLa cells (IC50 = 18 µg/mL), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model[1].
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COTC | COTC is a bacterial metabolite with anticancer activity that is found in S. griseosporeus. COTC inhibits glyoxalase in the presence of glutathione (GSH). COTC also inhibits the proliferation of HeLa cells (IC50 = 18 µg/mL), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model. | |||||||||||||||||||||
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References
Keywords
