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Art. -Nr.: HY-182694

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α7 nAChR Modulator-4

α7 nAChR Modulator-4 is a positive allosteric modulator of α7 nAChR, with an EC₅₀ of 910 nM. α7 nAChR Modulator-4 interacts with α7 nAChR to trigger downstream effects associated with inflammatory regulation. α7 nAChR Modulator-4 can be used in the research of Alzheimer's disease, Parkinson's disease and schizophrenia.

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CAS. Nr.: 2135284-68-1
Formel: C₁₄H₁₅F₂N₃O₃S
Molecular Weight:343.35

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

α7 nAChR Modulator-4 Chemical Structure

CAS. Nr.: 2135284-68-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

α7 nAChR Modulator-4 (EXAMPLE 7) exerts positive allosteric modulation on α7 nAChR, with an EC₅₀ value of 910 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2135284-68-1
Molecular Weight 343.35
Formel C₁₄H₁₅F₂N₃O₃S
SMILES

FC1([C@H](C2=NC(C(C)C)=NO2)[C@H]1C3=CC=C(C=C3)S(N)(=O)=O)F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Brendan M. Crowley, et al. Allosteric modulators of nicotinic acetylcholine receptors. WO2017165256A1. 2018-09-22.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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