Rivaroxaban impurity 50
Based on 1 Customer Validation
Rivaroxaban impurity 50 (thiophene-2-carboxylate) is an impurity of Rivaroxaban.
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- Reinheit: 99.94%
- CAS. Nr.: 527-72-0
- Formel: C5H4O2S
- Molecular Weight:128.15
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Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-5-2 | EC50 |
0.3 μM
Compound: Thiophene carboxylic acid
|
Antiviral activity against Hepatitis C virus genotype 1b infected in human Huh5-2 cells assessed as reduction in replicon RNA after 4 days by luciferase assay
Antiviral activity against Hepatitis C virus genotype 1b infected in human Huh5-2 cells assessed as reduction in replicon RNA after 4 days by luciferase assay
|
[PMID: 18625766] |
Chemical Information
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CAS. Nr. 527-72-0
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Appearance Solid
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Molecular Weight 128.15
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Formel C5H4O2S
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SMILES
O=C(O)C=1SC=CC1
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Synonyms
thiophene-2-carboxylate
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (780.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (245 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8034 mL | 39.0168 mL | 78.0336 mL | 195.0839 mL |
| 5 mM | 1.5607 mL | 7.8034 mL | 15.6067 mL | 39.0168 mL | |
| 10 mM | 0.7803 mL | 3.9017 mL | 7.8034 mL | 19.5084 mL | |
| 15 mM | 0.5202 mL | 2.6011 mL | 5.2022 mL | 13.0056 mL | |
| 20 mM | 0.3902 mL | 1.9508 mL | 3.9017 mL | 9.7542 mL | |
| 25 mM | 0.3121 mL | 1.5607 mL | 3.1213 mL | 7.8034 mL | |
| 30 mM | 0.2601 mL | 1.3006 mL | 2.6011 mL | 6.5028 mL | |
| 40 mM | 0.1951 mL | 0.9754 mL | 1.9508 mL | 4.8771 mL | |
| 50 mM | 0.1561 mL | 0.7803 mL | 1.5607 mL | 3.9017 mL | |
| 60 mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 3.2514 mL | |
| 80 mM | 0.0975 mL | 0.4877 mL | 0.9754 mL | 2.4385 mL | |
| 100 mM | 0.0780 mL | 0.3902 mL | 0.7803 mL | 1.9508 mL |