Aqp9 - aquaporin 9 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65054

Summary

Enables water channel activity. Involved in canalicular bile acid transport and water transport. Located in basolateral plasma membrane and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in kidney disease. Orthologous to human AQP9 (Aquaporin 9). [provided by Alliance of Genome Resources, Apr 2022]

Aqp9 Products (1)

mRNA Protein Name
NM_022960.2 NP_075249.1 aquaporin-9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables polyol transmembrane transporter activity IDA
IDA: Inferred from direct assay
9733774 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
25270793 RGD
enables purine nucleobase transmembrane transporter activity IDA
IDA: Inferred from direct assay
9733774 RGD
enables pyrimidine nucleobase transmembrane transporter activity IDA
IDA: Inferred from direct assay
9733774 RGD
enables urea transmembrane transporter activity IDA
IDA: Inferred from direct assay
9733774 RGD
enables water channel activity IDA
IDA: Inferred from direct assay
11932260 RGD
Biological Process GO Annotation Evidence References Source
involved in amine transport IDA
IDA: Inferred from direct assay
9733774 RGD
involved in canalicular bile acid transport IDA
IDA: Inferred from direct assay
11932260 RGD
involved in polyol transmembrane transport IDA
IDA: Inferred from direct assay
9733774 RGD
involved in purine nucleobase transport IDA
IDA: Inferred from direct assay
9733774 RGD
involved in pyrimidine nucleobase transport IDA
IDA: Inferred from direct assay
9733774 RGD
involved in response to pain IMP
IMP: Inferred from mutant phenotype
31746418 RGD
involved in water transport IDA
IDA: Inferred from direct assay
11932260 RGD
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
11932260 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aquaporin-9

  • AQP-9

  • aquaglyceroporin-9

  • neutral solute channel aquaporin 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-126073 DFP00173 99.46% Unkown
HY-161834 RG100204 Inhibitor 99.50% Unkown
HY-126074 Z433927330 98.20% Unkown
HY-148600 HTS13286 Inhibitor 98.98% Unkown
HY-148823 RF03176 Inhibitor / Unkown
HY-RS00881 AQP9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17944 Aqp9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24415 Aqp9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aqp9 NCBI NCBI:366