1. Membrane Transporter/Ion Channel Immunology/Inflammation
  2. Aquaporin NO Synthase
  3. HTS13286

HTS13286 is a novel AQP9 inhibitor. HTS13286 prevents the LPS-induced increase of NO. HTS13286 reduces glucose output. HTS13286 can be used in the research of endotoxin shock.

For research use only. We do not sell to patients.

HTS13286

HTS13286 Chemical Structure

CAS No. : 727359-12-8

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Description

HTS13286 is a novel AQP9 inhibitor. HTS13286 prevents the LPS-induced increase of NO. HTS13286 reduces glucose output. HTS13286 can be used in the research of endotoxin shock[1].

Molecular Weight

415.52

Formula

C16H13N7OS3

CAS No.
SMILES

O=C(CSC1=NN=C(N1C)C2=CC=NC=C2)NC3=NN=C(C4=CC=CS4)S3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 4 mg/mL (9.63 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4066 mL 12.0331 mL 24.0662 mL
5 mM 0.4813 mL 2.4066 mL 4.8132 mL
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4066 mL 12.0331 mL 24.0662 mL 60.1656 mL
5 mM 0.4813 mL 2.4066 mL 4.8132 mL 12.0331 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HTS13286
Cat. No.:
HY-148600
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