Dipropofol (Standard)
Dipropofol (Standard) is the analytical standard of Dipropofol. This product is intended for research and analytical applications. Dipropofol is a dimeric derivative of Propofol (HY-B0649) with antioxidant and antibacterial activities. Dipropofol terminates free radical chain reactions, scavenges DPPH free radicals and inhibits lipid peroxidation. Dipropofol protects cells from death induced by glutamate, Aβ(25-35) and buthionine sulfoximine, and increases the survival rate of mice exposed to oxygen. Dipropofol selectively activates tonic GABAA currents, hyperpolarizes resting membrane potential, reduces action potential firing, and alleviates the severity of seizures induced by Kainic acid. Dipropofol can be used in the research of Gram-positive bacterial infections, Alzheimer's disease, cerebral ischemia-related neuronal injury, oxygen toxicity and temporal lobe epilepsy.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 2416-95-7
- Formula: C24H34O2
- Molecular Weight:354.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2416-95-7
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Molecular Weight 354.53
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Formula C24H34O2
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SMILES
OC1=C(C(C)C)C=C(C2=CC(C(C)C)=C(O)C(C(C)C)=C2)C=C1C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ogata M, et al. Antioxidant activity of propofol and related monomeric and dimeric compounds. Chemical & pharmaceutical bulletin. 2005 Mar;53(3):344-6. [Content Brief]
[2]. Ogata M, et al. [Antioxidant and antibacterial activities of dimeric phenol compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2008 Aug;128(8):1149-58. [Content Brief]
[3]. Zhang J, et al. Anticonvulsant effect of dipropofol by enhancing native GABA currents in cortical neurons in mice. J Neurophysiol. 2018 Sep 1;120(3):1404-1414. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)