Triphenylmethanol
Based on 1 Customer Validation
Triphenylmethanol is a specific clathrate host for methanol and dimethyl sulphoxide. Triphenylmethanol inhibits neoplastic transformation of cells.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 76-84-6
- Formula: C19H16O
- Molecular Weight:260.34
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
2 μM
Compound: 7
|
Mitogen-induced cell proliferation assay to evaluate the antiproliferative effect in NIH 3T3 cells
Mitogen-induced cell proliferation assay to evaluate the antiproliferative effect in NIH 3T3 cells
|
[PMID: 14698156] |
Chemical Information
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CAS No. 76-84-6
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Appearance Solid
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Molecular Weight 260.34
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Formula C19H16O
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Color White to light yellow
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SMILES
OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
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Synonyms
Trt-OH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 50 mg/mL (192.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8411 mL | 19.2057 mL | 38.4113 mL | 96.0283 mL |
| 5 mM | 0.7682 mL | 3.8411 mL | 7.6823 mL | 19.2057 mL | |
| 10 mM | 0.3841 mL | 1.9206 mL | 3.8411 mL | 9.6028 mL | |
| 15 mM | 0.2561 mL | 1.2804 mL | 2.5608 mL | 6.4019 mL | |
| 20 mM | 0.1921 mL | 0.9603 mL | 1.9206 mL | 4.8014 mL | |
| 25 mM | 0.1536 mL | 0.7682 mL | 1.5365 mL | 3.8411 mL | |
| 30 mM | 0.1280 mL | 0.6402 mL | 1.2804 mL | 3.2009 mL | |
| 40 mM | 0.0960 mL | 0.4801 mL | 0.9603 mL | 2.4007 mL | |
| 50 mM | 0.0768 mL | 0.3841 mL | 0.7682 mL | 1.9206 mL | |
| 60 mM | 0.0640 mL | 0.3201 mL | 0.6402 mL | 1.6005 mL | |
| 80 mM | 0.0480 mL | 0.2401 mL | 0.4801 mL | 1.2004 mL | |
| 100 mM | 0.0384 mL | 0.1921 mL | 0.3841 mL | 0.9603 mL |