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Cat. No.: HY-184912

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ZL-A8 -C8-OH

ZL-A8-C8-OH is a synthetic E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates). ZL-A8-C8-OH can be used for the synthesis of PROTAC JHK-02-108-2 (HY-184910).

For research use only. We do not sell to patients.

Formula: C₂₃H₃₂N₄O₆
Molecular Weight:460.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ZL-A8 -C8-OH Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

ZL-A8-C8-OH is a synthetic E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates). ZL-A8-C8-OH can be used for the synthesis of PROTAC JHK-02-108-2 (HY-184910)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

In Vitro

ZL-A8-C8-OH is a synthetic E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC JHK-02-108-2 (HY-184910)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 460.52
Formula C₂₃H₃₂N₄O₆
SMILES

O=C(NCCCCCCCCO)COC1=CC=C(C(N2C)=C1)N(C(CC3)C(NC3=O)=O)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kim JH, et al. A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition. Journal of the American Chemical Society. 2026 Jul 08;148(26):27951-27964. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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ZL-A8 -C8-OH

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ZL-A8 -C8-OH Related Classifications

HY-184912 Related Classifications