N2-MIE-dG
N2-MIE-dG is the major DNA adduct formed after the activation of methyleugenol (ME) by SULT. N2-MIE-dG serves as a key biomarker for genotoxicity, metabolic activation, and potential carcinogenic risk.
For research use only. We do not sell to patients.
- CAS No.: 1399244-45-1
- Formula: C21H25N5O6
- Molecular Weight:443.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Under mutagenicity testing conditions, N2-MIE-dG is the predominant adduct formed in SULT-expressing *Salmonella typhimurium*[1].
N2-MIE-dG is abundantly formed in herring sperm DNA incubated with (±)-1'-acetoxymethyleugenol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1399244-45-1
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Molecular Weight 443.45
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Formula C21H25N5O6
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SMILES
O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)NC(NC/C=C/C4=CC=C(OC)C(OC)=C4)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N2-MIE-dG Related Classifications
HY-185917 Related Classifications
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