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Referencia número: HY-144466

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IDO1-IN-16

IDO1-IN-16 (I-1) is an IDO1 inhibitor targeting holo-IDO1, with an IC₅₀ of 127 nM.

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No. CAS: 2677054-63-4
Fòrmula: C₂₅H₃₅BrFN₅O₂
Peso molecular:536.48

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

IDO1-IN-16 Chemical Structure

No. CAS: 2677054-63-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Descripciòn
- IC₅₀ & Target
Chemical Information
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Actividad biológica

Descripciòn

IDO1-IN-16 (I-1) is an IDO1 inhibitor targeting holo-IDO1, with an IC₅₀ of 127 nM^[1].

IC₅₀ & Target^[1]

IDO1

127 nM (IC₅₀)

Ver todos los productos específicos de isoformas Indoleamine 2,3-Dioxygenase (IDO) :

Chemical Information

No. CAS 2677054-63-4
Peso molecular 536.48
Fòrmula C₂₅H₃₅BrFN₅O₂
SMILES

O=C(NCCC)NC1=CC(/C(NO)=N\C2=CC=C(C(Br)=C2)F)=CC=C1N(CC(C)C)CC(C)C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Yunze Wu, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021 Nov 15;52:128373. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
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IDO1-IN-16

Ver todos los productos específicos de isoformas Indoleamine 2,3-Dioxygenase (IDO)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

IDO1-IN-16 Related Classifications

HY-144466 Related Classifications