2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Fadolmidine hydrochloride

Fadolmidine hydrochloride is a novel, selective α2-adrenoceptor (α2-AR) agonist with EC50 values of 0.4 nM, 4.9 nM and 0.5 nM for 2A, 2B and 2C, respectively. Fadolmidine hydrochloride has been effective against various submodalities of pain such as heat pain, mechanical pain, and visceral pain. Fadolmidine hydrochloride inhibits also electrically evoked contractions in rat vas deferens.

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Fadolmidine hydrochloride

Fadolmidine hydrochloride Chemical Structure

CAS No. : 189353-32-0

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Fadolmidine hydrochloride Related Antibodies

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Description

Fadolmidine hydrochloride is a novel, selective α2-adrenoceptor (α2-AR) agonist with EC50 values of 0.4 nM, 4.9 nM and 0.5 nM for 2A, 2B and 2C, respectively. Fadolmidine hydrochloride has been effective against various submodalities of pain such as heat pain, mechanical pain, and visceral pain. Fadolmidine hydrochloride inhibits also electrically evoked contractions in rat vas deferens[1][2].

IC50 & Target[1]

α2-adrenergic receptor

 

Molecular Weight

250.72

Formula

C13H15ClN2O
CAS No.
SMILES

OC1=CC=C2C(C(CC2)CC3=CN=CN3)=C1.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Fadolmidine hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fadolmidine189353-32-0Adrenergic ReceptorBeta Receptorheat painmechanical painand visceral painInhibitorinhibitorinhibit

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