Losoxantrone
Losoxantrone (CI 941) is a DNA-binding agent. Losoxantrone has broad-spectrum antitumour activity. Losoxantrone induces dose-dependent leukopenia.
For research use only. We do not sell to patients.
- CAS No.: 88303-60-0
- Formula: C22H27N5O4
- Molecular Weight:425.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
0.12 μM
Compound: Losoxantrone
|
Growth inhibition of human K562 cells after 72 hrs by MTS method
Growth inhibition of human K562 cells after 72 hrs by MTS method
|
[PMID: 18258442] |
Chemical Information
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CAS No. 88303-60-0
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Molecular Weight 425.48
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Formula C22H27N5O4
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SMILES
O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCNCCO)C=CC=C2O
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Synonyms
CI 941; DuP-941; Biantrazole
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)