11-Dehydrodexamethasone
Based on 1 Customer Validation
11-Dehydrodexamethasone, Dexamethasone (HY-14648) derivative, is a substrate for 11β-hydroxysteroid dehydrogenase (11β-HSD) 1/2. 11-Dehydrodexamethasone undergoes conversion to Dexamethasone via reductive activity of 11β-HSD.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.19%
- No. CAS: 2964-81-0
- Fòrmula: C22H27FO5
- Peso molecular:390.45
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
11-Dehydrodexamethasone (20 ng; 10 min) acts as a substrate for both 11β-HSD1 (rat liver) and 11β-HSD2 (rat renal cortex, human kidney) isozymes, undergoing conversion to Dexamethasone (HY-14648) with mean conversion rates of 65%, 53.5%, and 69% respectively in the tested tissue homogenates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2964-81-0
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Appearance Solid
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Peso molecular 390.45
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Fòrmula C22H27FO5
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Color White to off-white
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SMILES
F[C@@]12[C@](CCC([C@@]2(C=C3)C)=CC3=O)([H])[C@@]4([H])[C@](CC1=O)([C@](O)([C@@H](C4)C)C(CO)=O)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
11-Dehydrodexamethasone Related Classifications
HY-W754031 Related Classifications
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