DOTA-NOC
Based on 1 Customer Validation
DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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- Pureza: 99.22%
- No. CAS: 619300-53-7
- Fòrmula: C69H94N14O17S2
- Peso molecular:1455.70
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas Radionuclide-Drug Conjugates (RDCs)
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Actividad biológica
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RDC Peptide |
Affinity profiles (IC50(μM)) for human somatostatin receptor (SST) 1-5[1].
| Compound | hsst1 | hsst2 | hsst3 | hsst4 | hsst5 |
| InIII-DOTA-NOC | >10000 | 2.9 | 8 | 227 | 11.2 |
| YIII-DOTA-NOC | >10000 | 3.3 | 26 | >10000 | 10.4 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 619300-53-7
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Appearance Solid
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Peso molecular 1455.70
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Fòrmula C69H94N14O17S2
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Color White to off-white
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Synonyms
DOTA-Nal3-octreotide
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Sequence
DOTA-{d-Phe}-Cys-{Nal}-{d-Trp}-Lys-Thr-Cys-{Threoninol} (Disulfide bridge: Cys2-Cys7)
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Sequence Shortening
DOTA-{d-Phe}-C-{Nal}-{d-Trp}-KTC-{Threoninol} (Disulfide bridge: Cys2-Cys7)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 50 mg/mL (34.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6870 mL | 3.4348 mL | 6.8695 mL | 17.1739 mL |
| 5 mM | 0.1374 mL | 0.6870 mL | 1.3739 mL | 3.4348 mL | |
| 10 mM | 0.0687 mL | 0.3435 mL | 0.6870 mL | 1.7174 mL | |
| 15 mM | 0.0458 mL | 0.2290 mL | 0.4580 mL | 1.1449 mL | |
| 20 mM | 0.0343 mL | 0.1717 mL | 0.3435 mL | 0.8587 mL | |
| 25 mM | 0.0275 mL | 0.1374 mL | 0.2748 mL | 0.6870 mL | |
| 30 mM | 0.0229 mL | 0.1145 mL | 0.2290 mL | 0.5725 mL |
DOTA-NOC Related Classifications
HY-P2112 Related Classifications
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