Tpr - translocated promoter region, nuclear basket protein Gene

Also Known as 2610029M07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108989

Summary

Predicted to enable several functions, including dynein complex binding activity; mitogen-activated protein kinase binding activity; and protein homodimerization activity. Predicted to be a structural constituent of nuclear pore. Involved in cellular response to interferon-alpha. Located in nuclear envelope; nuclear inclusion body; and nuclear periphery. Part of nuclear pore. Is expressed in several structures, including alimentary system; brain ventricular layer; genitourinary system; olfactory epithelium; and vibrissa. Orthologous to human TPR (translocated promoter region, nuclear basket protein). [provided by Alliance of Genome Resources, Apr 2022]

Tpr Products (1)

mRNA Protein Name
NM_133780.3 NP_598541.3 nucleoprotein TPR

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
12513910 MGI
Biological Process GO Annotation Evidence Referencias Source
involved in cellular response to interferon-alpha IDA
IDA: Inferred from direct assay
12513910 MGI
Cellular Component GO Annotation Evidence Referencias Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
12424524 MGI
located in nuclear inclusion body IDA
IDA: Inferred from direct assay
12513910 MGI
located in nuclear periphery IDA
IDA: Inferred from direct assay
22401879 MGI
part of nuclear pore IDA
IDA: Inferred from direct assay
12513910 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleoprotein TPR

  • NPC-associated intranuclear protein

  • nuclear pore complex-associated protein Tpr

  • translocated promoter region and nuclear basket protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-W1128879 XMU-MP-8 Degrader 99.23% Unkown
HY-103241 Ro 90-7501 98.50% Unkown
HY-175552 CHIPOpt Inhibitor 99.49% Unkown
HY-125759 3-Phenyltoxoflavin Inhibitor 99.76% Unkown
HY-P1896 Hsp70-derived octapeptide 98.01% Unkown
HY-179343 Hsp90-IN-43 Inhibitor / Unkown
HY-P11185 Hsp90β decapeptide / Unkown
HY-RS14946 TPR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18457 Tpr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24938 Tpr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpr NCBI NCBI:7175