Hsp90-IN-43
Hsp90-IN-43 (Compound 12) is a Hsp90-TPR2A interaction inhibitor with an IC50 of 360 nM and a Kd of 928 nM. Hsp90-IN-43 effectively inhibits the proliferation of BT474 cells. Hsp90-IN-43 can be used for the study of breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 164520-05-2
- Formula: C14H13N5O2
- Molecular Weight:283.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
0.9 μM
Compound: 286e
|
Antiproliferative activity against human BT-474 cells assessed as inhibition of cell growth
Antiproliferative activity against human BT-474 cells assessed as inhibition of cell growth
|
[PMID: 28851503] |
Chemical Information
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CAS No. 164520-05-2
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Molecular Weight 283.29
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Formula C14H13N5O2
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SMILES
O=C1N=C2C(C(N1C)=O)=NC(C3=CC=CC=C3)=NN2CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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