BMPR2 - bone morphogenetic protein receptor type 2 Gene

Also Known as BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 659

About BMPR2

Cytogenetic location: 2q33.1-q33.2 Genomic coordinates (GRCh38): 2:202,376,327-202,567,749 (from NCBI)

This gene has 3 transcripts (splice variants), 265 orthologues, 11 paralogues and is associated with 5 phenotypes. Ubiquitous expression in lung (RPKM 16.2), brain (RPKM 15.1) and 24 other tissues.

Summary

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta Superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020]

BMPR2 Products (3)

mRNA	Protein	Name
XM_011511687.2	XP_011509989.1	bone morphogenetic protein receptor type-2 isoform X1
NM_001204.7	NP_001195.2	bone morphogenetic protein receptor type-2 precursor
NM_033346.2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables BMP binding	IPI IPI: Inferred from physical interaction	21976273	GOA
enables activin receptor activity, type II	IDA IDA: Inferred from direct assay	19366699	GOA
enables cadherin binding	IPI IPI: Inferred from physical interaction	26598555	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	12045205	GOA
enables protein tyrosine kinase binding	IPI IPI: Inferred from physical interaction	26598555	GOA

Biological Process GO Annotation	Evidence	Referencias	Source
involved in BMP signaling pathway	IDA IDA: Inferred from direct assay	18436533	GOA
involved in BMP signaling pathway	IGI IGI: Inferred from genetic interaction	18382765	GOA
involved in BMP signaling pathway	IMP IMP: Inferred from mutant phenotype	9442116	GOA
involved in cell surface receptor protein serine/threonine kinase signaling pathway	IDA IDA: Inferred from direct assay	12045205	GOA
involved in cellular response to BMP stimulus	IMP IMP: Inferred from mutant phenotype	18326817	GOA
involved in cellular response to starvation	IEP IEP: Inferred from expression pattern	15657086	GOA
involved in chondrocyte development	IMP IMP: Inferred from mutant phenotype	9442116	GOA
involved in endothelial cell apoptotic process	IMP IMP: Inferred from mutant phenotype	25187962	GOA
involved in endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	25187962	GOA
involved in lung vasculature development	IMP IMP: Inferred from mutant phenotype	17992660	GOA
involved in negative regulation of cell growth	IDA IDA: Inferred from direct assay	12819188	GOA
involved in negative regulation of chondrocyte proliferation	IMP IMP: Inferred from mutant phenotype	9442116	GOA
involved in negative regulation of smooth muscle cell proliferation	IMP IMP: Inferred from mutant phenotype	18382765	GOA
involved in negative regulation of systemic arterial blood pressure	IMP IMP: Inferred from mutant phenotype	18364108	GOA
involved in osteoblast differentiation	IMP IMP: Inferred from mutant phenotype	22684006	GOA
acts upstream of or within positive regulation of SMAD protein signal transduction	IGI IGI: Inferred from genetic interaction	18382765	GOA
involved in positive regulation of SMAD protein signal transduction	IMP IMP: Inferred from mutant phenotype	17992660	GOA
involved in positive regulation of bone mineralization	IMP IMP: Inferred from mutant phenotype	18436533	GOA
involved in positive regulation of epithelial cell migration	IDA IDA: Inferred from direct assay	12819188	GOA
acts upstream of positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	22684006	GOA
involved in positive regulation of osteoblast differentiation	IMP IMP: Inferred from mutant phenotype	18436533	GOA
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	12045205	GOA
involved in regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	11502704	GOA
involved in regulation of lung blood pressure	IMP IMP: Inferred from mutant phenotype	18364108	GOA

Cellular Component GO Annotation	Evidence	Referencias	Source
located in adherens junction	IDA IDA: Inferred from direct assay	25468996	GOA
colocalizes with caveola	IMP IMP: Inferred from mutant phenotype	15657086	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	12045205	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BMPR2 Protein Structure

Activin_recp

Pkinase

0
200
400
600
800
1038 a.a.

Protein Preferred Names	Protein Names
bone morphogenetic protein receptor type-2	BMP type II receptor BMP type-2 receptor bone morphogenetic protein receptor type II bone morphogenetic protein receptor, type II (serine/threonine kinase) type II activin receptor-like kinase type II receptor for bone morphogenetic protein-4

BMPR2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Referencias
Intra	BMPR2	Q13873	YWHAE	Homo sapiens	P62258	Crosslink	36931259
Cross	BMPR2	Q13873	Prkcb	Mus musculus	P68404	Pull Down	15188402
Cross	BMPR2	Q13873	C4bpa	Mus musculus	P08607	Pull Down	15188402
Intra	BMPR2	Q13873	GDF5	Homo sapiens	P43026	SPR	19229295

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant BMPR2 Proteins

Referencia número	Nombre del producto	Accession	Pureza
HY-P7669	BMPR-II Protein, Human (HEK293, His)	Q13873-1 (S27-I151)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72855	BMPR-II Protein, Human (HEK293, His-Fc)	Q13873-1 (S27-I151)	≥ 90%, as determined by reducing SDS-PAGE.

BMPR2 Antibodies

Referencia número	Nombre del producto	Aplicación	Reactivity
HY-P84557	BMPR2 Antibody (YA4254)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P84557A	BMPR2 Antibody (YA4254)(PBS only)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P85062	BMPR2 Antibody (YA4754)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat, Monkey

Related Diseases

Diseases	Alias
Juvenile Polyposis/Hereditary Hemorrhagic Telangiectasia Syndrome	Juvenile Polyposis-Hereditary Hemorrhagic Telangiectasia Syndrome JPHT Jp/Hht Syndrome Juvenile Polyposis With Hereditary Hemorrhagic Telangiectasia Jps/Hht Telangiectasia, Hereditary Hemorrhagic, With Juvenile Polyposis Coli Polyposis, Generalized Juvenile, With Pulmonary Arteriovenous Malformation Jp-Hht JP/HHT Polyposis, Juvenile/Hereditary Hemorrhagic Telangiectasia Syndrome
Submucous Uterine Fibroid	Submucous Leiomyoma Of Uterus
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Congenital Anomaly Of Heart Heart Defect Heart Malformation Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Colon Adenocarcinoma	Adenocarcinoma Of Colon Adenocarcinoma Of The Colon Colonic Adenocarcinoma
Atrial Heart Septal Defect	Atrial Septal Defect Atrial Septal Defects Atrioseptal Defect Auricular Septal Defect Congenital Atrial Septal Defect Interatrial Septal Defect Interauricular Septal Defect Heart Septal Defects, Atrial Septal Defect, Atrial
Pulmonary Venoocclusive Disease	Pulmonary Veno-Occlusive Disease Obstructive Disease Of The Pulmonary Veins Pvod Isolated Pulmonary Venous Sclerosis Venous Form Of Primary Pulmonary Hypertension Pulmonary Venoocclusive Disease 1, Autosomal Dominant
Hepatic Vascular Disease	Vascular Disorder Of Liver
Arteriovenous Malformation	Arteriovenous Malformations Arteriovenous Hemangioma Cirsoid Aneurysm Racemose Aneurysm Racemose Angioma Racemose Hemangioma Congenital Arteriovenous Malformation
Mixed Connective Tissue Disease	Sharp Syndrome Mctd Connective Tissue Disease Overlap Syndrome Mixed Collagen Vascular Disease Mctd - [Mixed Connective Tissue Disease]
Pulmonary Hypertension	Primary Pulmonary Hypertension Hypertension Pulmonary Hypertension, Pulmonary Idiopathic Pulmonary Hypertension Idiopathic Pulmonary Arterial Hypertension Pulmonary Htn - [Hypertension]
Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension	Small Patella Syndrome Ischiopatellar Dysplasia Coxopodopatellar Syndrome Scott-Taor Syndrome Sps Ischiocoxopodopatellar Syndrome Patella Aplasia, Coxa Vara, And Tarsal Synostosis ICPPS Congenital Coxa Vara, Patella Aplasia And Tarsal Synostosis Coxo-Podo-Patellar Syndrome Patella Aplasia, Coxa Vara, Tarsal Synostosis Coxopodipatellar Syndrome
Pulmonary Valve Insufficiency	Pulmonary Regurgitation Pulmonary Incompetence Pulmonary Incompetence, Non-Rheumatic Pulmonary Insufficiency Following Trauma And Surgery Pulmonary Regurg. Pulmonic Insufficiency Pulmonic Valve Regurgitation Pulmonary Valve Incompetence Pulmonary Valve Incompetency Pulmonary Valvular Insufficiency Pulmonary Valvular Regurgitation Pulmonary Valvular Incompetency Pulmonary Valve Incompetence Nos Annular Incompetency Pulmonary Valve Incompetent Pulmonary Valve Graham Steell Murmur Pulmonary Valvular Incompetence
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Cryptogenic Fibrosing Alveolitis Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Drug- Or Toxin-Induced Pulmonary Arterial Hypertension	Drug- Or Toxin-Induced Pah
Patent Foramen Ovale	Atrial Septal Defect Within Oval Fossa Foramen Ovale Patent Ostium Secundum Atrial Septal Defect Atrial Septal Defect, Ostium Secundum Type Foramen Ovale, Patent Defect, Patent Or Persistent, Ostium Secundum Ostium Secundum Type Atrial Septal Defect Persistent Ostium Secundum Asd Ostium Secundum Type Ostium Secundum Asd Osasd Asd, Ostium Secundum Type Pfo - [Patent Foramen Ovale] Open Foramen Ovale Open Oval Foramen Persistent Foramen Ovale Secundum Atrial Septal Defect
Hepatopulmonary Syndrome
Pulmonary Venoocclusive Disease 1, Autosomal Dominant	Pulmonary Venoocclusive Disease 1 PVOD1 Pvod Pulmonary Veno-Occlusive Disease Pulmonary Veno-Occlusive Disease, Type 1
Tricuspid Valve Disease	Rheumatic Tricuspid Valve Disease Disease Of Tricuspid Valve Rh. Tricuspid Valve Disease Rheumatic Disease Of Tricuspid Valve Tricuspid Disease Tricuspid Valve Disorder
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Brachydactyly, Type A2	Brachydactyly Type A2 BDA2 Mohr-Wriedt Type Brachydactyly Brachymesophalangy Ii Brachymesophalangy Type 2 Brachymesophalangy 2 Brachydactyly, Mohr-Wriedt Type Brachydactyly A2
Tricuspid Valve Insufficiency	Tricuspid Regurgitation Tricuspid Valve Regurgitation Tricuspid Incompetence Tr - [Tricuspid Regurgitation] Tricuspid Valve Incompetency Tricuspid Valve Annular Incompetency
Genetic Non-Acquired Premature Ovarian Failure
Fibrodysplasia Ossificans Progressiva	Myositis Ossificans Progressiva Progressive Myositis Ossificans FOP Progressive Ossifying Myositis Myositis Ossificans Stone Man Syndrome Man Of Stone Myositis Ossificans Progressive Diffuse Progressive Ossifying Polymyositis Fibrodysplasia Ossificans Congenita Myositis Ossificans Progressiva, Site Unspecified Münchmeyer Disease Fop - [Fibrodysplasia Ossificans Progressiva] Progressive Myositis Ossificans Calcification
Portal Hypertension	Hypertension, Portal Hypertension Portal Pht - [Portal Hypertension] Portal Htn
Pulmonary Arterial Hypertension Associated With Congenital Heart Disease	Pah Associated With Congenital Heart Disease
Glycogen Storage Disease	Glycogenosis Glycogenoses Gsd Storage Disease, Glycogen Gsd - [Glycogen Storage Disease] Glycogen Thesaurismosis Diffuse Glycogenosis Generalised Glycogen Storage Disease Generalised Glycogenosis Generalised Glycogen Storage Disease Of Infants Glycogen Synthase Deficiency
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Diaphragmatic Hernia, Congenital	Congenital Diaphragmatic Hernia Diaphragmatic Hernia Hernia, Congenital Diaphragmatic 1 Cdh Congenital Diaphragmatic Defect Hernia, Diaphragmatic Dih Hernia, Congenital Diaphragmatic Hcd Diaphragmatic Defect, Congenital Diaphragm, Unilateral Agenesis Of Hemidiaphragm, Agenesis Of Agenesis Of Hemidiaphragm Unilateral Agenesis Of Diaphragm Hernia Diaphragmatic Hernia Diaphragmatic Congenital Hiatus Hernia Oesophageal Hiatus Hernia Paraoesophageal Hernia Sliding Hiatus Hernia Congenital Diaphragm Hernia Congenital Diaphragm Defect With Hernia Gross Congenital Diaphragm Defect
Patent Ductus Arteriosus 1	Patent Ductus Arteriosus PDA1 Pda Ductus Arteriosus, Patent Patent Ductus Arteriosus, Susceptibility To Patent Ductus Botalli Patency Of The Ductus Arteriosus Patent Ductus Arteriosus Familial Ductus Arteriosus Patent Patent Ductus Arteriosus - Persisting Type
Fragile X Syndrome	FXS Martin-Bell Syndrome Fraxa Syndrome Marker X Syndrome X-Linked Mental Retardation And Macroorchidism Fragile X Mental Retardation Syndrome Fra Syndrome Mental Retardation, X-Linked, Associated With Marxq28 Frax Syndrome Symptomatic Form Of Fragile X Syndrome In Female Carriers Fragile-X Syndrome Fraxe Syndrome
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Spinal Cord Vascular Diseases Vascular Tissue Disease Vascular Anomaly
Juvenile Polyposis Syndrome	JPS Juvenile Intestinal Polyposis Jip Pji Juvenile Gastrointestinal Polyposis Juvenile Polyposis Polyposis, Juvenile Intestinal Polyposis, Familial, Of Entire Gastrointestinal Tract Polyposis Familial Of Entire Gastrointestinal Tract Polyposis Juvenile Intestinal Polyposis Syndrome, Juvenile
Multiple Synostoses Syndrome	Symphalangism-Brachydactyly Syndrome Deafness-Hermann Type Symphalangism Syndrome Facio-Audio-Symphalangism Hearing Loss-Hermann Type Symphalangism Syndrome Wl Syndrome Multiple Synostosis Syndrome
Aortic Valve Prolapse
Idiopathic/Heritable Pulmonary Arterial Hypertension	Idiopathic And/Or Familial Pulmonary Arterial Hypertension
Hereditary Hemorrhagic Telangiectasia	Rendu-Osler-Weber Disease Hht Osler-Weber-Rendu Disease Telangiectasia, Hereditary Hemorrhagic Osler Hemorrhagic Telangiectasia Syndrome Orw Disease Osler Weber Rendu Syndrome Osler-Rendu-Weber Disease Osler-Weber-Rendu Syndrome Rendu-Osler Disease Telangiectasia Hereditary Hemorrhagic Telangiectasia Hemorrhagic, Hereditary Hht - [Hereditary Haemorrhagic Telangiectasia] Osler Haemorrhagic Telangiectasia Syndrome
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Heritable Pulmonary Arterial Hypertension	Fpah Familial Pulmonary Arterial Hypertension Hpah Hereditary Pulmonary Arterial Hypertension Familial Primary Pulmonary Hypertension
Pulmonary Hypertension, Primary, 1	Pulmonary Arterial Hypertension Pah Idiopathic Pulmonary Arterial Hypertension Idiopathic Pulmonary Hypertension Primary Pulmonary Hypertension PPH1 Pulmonary Hypertension, Familial Primary, 1, With Or Without Hht Pulmonary Hypertension, Primary, Fenfluramine Or Dexfenfluramine-Associated Pph Familial Primary Pulmonary Hypertension Sporadic Primary Pulmonary Hypertension Pht Fpah Familial Pulmonary Arterial Hypertension Hereditary Pulmonary Arterial Hypertension Heritable Pulmonary Arterial Hypertension Ayerza Syndrome Fpph Ppht Ipah Primary Pulmonary Arterial Hypertension Pulmonary Hypertension, Familial Primary Hypertension, Pulmonary, Primary, Type 1 Ayerza'S Syndrome Pah - [Pulmonary Arterial Hypertension] Arrillaga Ayerza Syndrome
Telangiectasis	Telangiectasia
Chronic Pulmonary Heart Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-15897	LDN-212854	Inhibitor	99.62%	Unkown
HY-164145	CDD-1653		99.38%	Unkown
HY-154970A	BMPR2-IN-1 TFA	Inhibitor	99.40%	Unkown
HY-154970	BMPR2-IN-1	Inhibitor	/	Unkown
HY-174416	Smurf1-IN-5	Inhibitor	/	Unkown
HY-RS01552	BMPR2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-171249	CDD-1431	Inhibitor	/	Unkown
HY-RS01553	Bmpr2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01554	Bmpr2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-171247	CDD-1281	Inhibitor	/	Unkown
HY-171248	CDD-1115	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	BMPR2	VGNC	VGNC:70268
Rattus norvegicus	BMPR2	RGD	RGD:71082
Bos taurus	BMPR2	VGNC	VGNC:26526
Canis familiaris	BMPR2	VGNC	VGNC:38486
Mus musculus	BMPR2	MGD	MGI:1095407
Felis catus	BMPR2	VGNC	VGNC:60139
Others	BMPR2	NCBI