CDD-1431
CDD-1431 is a low-nanomolar selective kinase inhibitors of BMPR2, with Kiapp value of 20.6 nM. CDD-1431 suppresses BRE-reporter activity, with an IC50 of 4.87 μM. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation.
For research use only. We do not sell to patients.
- CAS No.: 3034216-31-1
- Formula: C33H38N8O5S
- Molecular Weight:658.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
BMPR2: Kiapp value of 20.6 nM
Chemical Information
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CAS No. 3034216-31-1
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Molecular Weight 658.77
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Formula C33H38N8O5S
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SMILES
COC(C=N1)=C(N2CCN(C3=CC=CC(CNC(C4=CC=C(CCC(NC)=O)C=C4)=O)=C3)CC2)N=C1NC5=CC(S(=O)(N)=O)=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDD-1431 Related Classifications
HY-171249 Related Classifications
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