GLX481372
GLX481372 is a NADPH Oxidase (NOX) inhibitor. GLX481372 potently inhibits NOX4/5 activities with IC50 values of 0.68 and 0.57 μM. GLX481372 also has weak inhibitory activity against NOX1, NOX2, and NOX3, with IC50 values of 7, 16 and 3.2 μM respectively. GLX481372 can inhibit ROS production. GLX481372 can be used for the researches of inflammation, cardiovascular and metabolic disease, such as diabetes.
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- No. CAS: 1990478-58-4
- Fòrmula: C23H29N7
- Peso molecular:403.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Actividad biológica
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NOX5 0.57 μM (IC50) |
NOX4 0.68 μM (IC50) |
NOX3 3.2 μM (IC50) |
NOX1 7 μM (IC50) |
NOX2 16 μM (IC50) |
Chemical Information
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No. CAS 1990478-58-4
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Peso molecular 403.52
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Fòrmula C23H29N7
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SMILES
CC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC=C(C)C=C4)=N2)=CC=C1C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GLX481372 Related Classifications
HY-148936 Related Classifications
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