GUB10194
GUB10194 is a fully potent and selective GPR10 agonist with an EC50 of 15 nM. GUB10194 does not significantly affect body weight or food intake.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C85H148N24O23
- Peso molecular:1874.23
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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NPFF2-R > 5000 nM (EC50) |
GUB10194 (30 min) acts as a full, GPR10-selective agonist in Chem-1 cells expressing GPR10 (EC50 = 15 nM), with no activity detected in CHO-K1 cells expressing NPFF2R (EC50 > 5000 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J (male, 5 weeks old at purchase, diet-induced obese)[1]
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Dosage:1250 nmol/kg
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Administration:s.c.; twice daily
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Result:Did not significantly influence body weight or food intake during treatment or wash-out period.
Was detected in plasma samples collected 4 hours after the last dose on treatment day 6.
Chemical Information
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Peso molecular 1874.23
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Fòrmula C85H148N24O23
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Sequence
Ser-Arg-Gly-{Lys(AEEA-AEEA-γGlu-C18 diacid)}-Arg-Pro-Val-Gly-Arg-Phe-NH2
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Sequence Shortening
SRG-{Lys(AEEA-AEEA-γGlu-C18 diacid)}-RPVGRF-NH2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GUB10194 Related Classifications
HY-P11811 Related Classifications
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