Hippadine
Hippadine (Pratorine) is an alkaloid, which can be isolated from the plant Crinum macowanii. Hippadine exhibits heart-rate lowering and blood-pressure lowering effects in rats models with spontaneously hypertensive.
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- No. CAS: 52886-06-3
- Fòrmula: C16H9NO3
- Peso molecular:263.25
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
96 μM
Compound: 29
|
Growth inhibition of pro-apoptotic stimuli-resistant human A549 cells after 72 hrs by MTT assay
Growth inhibition of pro-apoptotic stimuli-resistant human A549 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| B16-F10 | GI50 |
34 μM
Compound: 29
|
Growth inhibition of pro-apoptotic stimuli-sensitive mouse B16F10 cells after 72 hrs by MTT assay
Growth inhibition of pro-apoptotic stimuli-sensitive mouse B16F10 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| Hs 683 | GI50 |
19 μM
Compound: 29
|
Growth inhibition of pro-apoptotic stimuli-sensitive human Hs683 cells after 72 hrs by MTT assay
Growth inhibition of pro-apoptotic stimuli-sensitive human Hs683 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| MCF7 | GI50 |
27 μM
Compound: 29
|
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| PC-3 | GI50 |
>100 μM
Compound: 29
|
Growth inhibition of human PC3 cells after 72 hrs by MTT assay
Growth inhibition of human PC3 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| SK-MEL-28 | GI50 |
>100 μM
Compound: 29
|
Growth inhibition of pro-apoptotic stimuli-resistant human SK-MEL-28 cells after 72 hrs by MTT assay
Growth inhibition of pro-apoptotic stimuli-resistant human SK-MEL-28 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| T98G | GI50 |
96 μM
Compound: 29
|
Growth inhibition of pro-apoptotic stimuli-resistant human T98G cells after 72 hrs by MTT assay
Growth inhibition of pro-apoptotic stimuli-resistant human T98G cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
| U-373MG ATCC | GI50 |
27 μM
Compound: 29
|
Growth inhibition of pro-apoptotic stimuli-resistant human U373 cells after 72 hrs by MTT assay
Growth inhibition of pro-apoptotic stimuli-resistant human U373 cells after 72 hrs by MTT assay
|
[PMID: 22019045] |
Chemical Information
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No. CAS 52886-06-3
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Peso molecular 263.25
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Fòrmula C16H9NO3
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SMILES
O=C1N2C3=C(C=CC=C3C4=C1C=C5C(OCO5)=C4)C=C2
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Synonyms
Pratorine
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Structure Classification
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)