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Referencia número: HY-155411

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HPSE1-IN-2

HPSE1-IN-2 (compound 2) is a Heparanase-1 (HPSE1) inhibitor that also inhibits exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA) activity.

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No. CAS: 2876926-27-9
Fòrmula: C₂₃H₂₄N₂O₆
Peso molecular:424.45

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

HPSE1-IN-2 Chemical Structure

No. CAS: 2876926-27-9

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- IC₅₀ & Target
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Actividad biológica

Descripciòn

HPSE1-IN-2 (compound 2) is a Heparanase-1 (HPSE1) inhibitor that also inhibits exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA) activity^[1].

IC₅₀ & Target

Heparanase-1 (HPSE1), exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)^[1]

Ver todos los productos específicos de isoformas Endogenous Metabolite :

Chemical Information

No. CAS 2876926-27-9
Peso molecular 424.45
Fòrmula C₂₃H₂₄N₂O₆
SMILES

CO[C@H]1[C@@H]([C@H](C2=NC(CCC3=CC(OC4=CC=CC=C4)=CC=C3)=CN2[C@@H]1C(O)=O)O)O
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543.

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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HPSE1-IN-2

Ver todos los productos específicos de isoformas Endogenous Metabolite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

HPSE1-IN-2 Related Classifications

HY-155411 Related Classifications