Methyl chlorogenate
Based on 1 Customer Validation
Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.28%
- No. CAS: 29708-87-0
- Fòrmula: C17H20O9
- Peso molecular:368.34
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
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| B16 | IC50 |
>40 μM
Compound: 2
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Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16 cells assessed as reduction in melanin formation
Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16 cells assessed as reduction in melanin formation
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[PMID: 28619537] |
| BV-2 | IC50 |
12.11 μM
Compound: 11
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Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 10 mins by Griess assay relative to control
Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 10 mins by Griess assay relative to control
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[PMID: 23462643] |
Chemical Information
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No. CAS 29708-87-0
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Appearance Solid
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Peso molecular 368.34
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Fòrmula C17H20O9
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Color White to off-white
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SMILES
COC([C@]1(C[C@H]([C@@H]([C@@H](C1)O)O)OC(/C=C/C2=CC(O)=C(C=C2)O)=O)O)=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 125 mg/mL (339.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Szymborska K, et al. Extraction with Acidified Methanol-An Easy and Effective Method of Methyl Chlorogenate Formation, as Studied by ESI-MS. Molecules. 2022 Nov 3;27(21):7543. [Content Brief]
[2]. Pang Y, et al. Inhibition of abnormally activated HIF-1α-GLUT1/3-glycolysis pathway enhances the sensitivity of hepatocellular carcinoma to 5-caffeoylquinic acid and its derivatives. Eur J Pharmacol. 2022 Apr 5;920:174844. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.7149 mL | 13.5744 mL | 27.1488 mL | 67.8721 mL |
| 5 mM | 0.5430 mL | 2.7149 mL | 5.4298 mL | 13.5744 mL | |
| 10 mM | 0.2715 mL | 1.3574 mL | 2.7149 mL | 6.7872 mL | |
| 15 mM | 0.1810 mL | 0.9050 mL | 1.8099 mL | 4.5248 mL | |
| 20 mM | 0.1357 mL | 0.6787 mL | 1.3574 mL | 3.3936 mL | |
| 25 mM | 0.1086 mL | 0.5430 mL | 1.0860 mL | 2.7149 mL | |
| 30 mM | 0.0905 mL | 0.4525 mL | 0.9050 mL | 2.2624 mL | |
| 40 mM | 0.0679 mL | 0.3394 mL | 0.6787 mL | 1.6968 mL | |
| 50 mM | 0.0543 mL | 0.2715 mL | 0.5430 mL | 1.3574 mL | |
| 60 mM | 0.0452 mL | 0.2262 mL | 0.4525 mL | 1.1312 mL | |
| 80 mM | 0.0339 mL | 0.1697 mL | 0.3394 mL | 0.8484 mL | |
| 100 mM | 0.0271 mL | 0.1357 mL | 0.2715 mL | 0.6787 mL |
Methyl chlorogenate Related Classifications
HY-N4168B Related Classifications
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