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Referencia número: HY-N3215

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Nagilactone C

Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines.

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No. CAS: 24338-53-2
Fòrmula: C₁₉H₂₂O₇
Peso molecular:362.37

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Nagilactone C Chemical Structure

No. CAS: 24338-53-2

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
AGS	IC₅₀	2.3 μM Compound: 7j	Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
HeLa	IC₅₀	3.3 μM Compound: 7j	Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
HepG2	IC₅₀	14 μM Compound: 7j	Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
MDA-MB-231	IC₅₀	5 μM Compound: 7j	Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
P388	IC₅₀	0.33 μg/mL Compound: 1	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 1800635]
PANC-1	IC₅₀	>40 μM Compound: 7j	Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]

Chemical Information

No. CAS 24338-53-2
Peso molecular 362.37
Fòrmula C₁₉H₂₂O₇
SMILES

C[C@@]1(C2=C3)[C@]4([H])[C@]([C@@H](O)[C@@H]5[C@H]1O5)(C(O[C@]4([H])[C@H](O)C2=C(C(C)C)OC3=O)=O)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. K Shrestha, et al. An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius. Phytomedicine. 2001 Nov;8(6):489-91. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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