Cytotoxic norditerpene lactones from Ileostylus micranthus

  • J Nat Prod. 1991 Sep-Oct;54(5):1326-30. doi: 10.1021/np50077a015.
S J Bloor  1 ,  B P Molloy
Affiliations
  • 1. DSIR Chemistry, Petone, New Zealand.
PMID: 1800635 DOI: 10.1021/np50077a015
Abstract

Three new compounds 2-4 and two known compounds 1 and 5 have been isolated from the cytotoxic fraction of an extract from a New Zealand mistletoe, Ileostylus micranthus. Compounds 1-5 are shown to be norditerpene lactones and have strong cytotoxicity. The compounds are proposed to have been assimilated by the mistletoe from the host tree, Podocarpus totara.