NBD-10007
NBD-10007 is a CD4 agonist. NBD-10007 has anti-HIV-1 viral activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1375736-65-4
- Fòrmula: C20H25ClN4O3S
- Peso molecular:436.96
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
>62 μM
Compound: 9, NBD-10007, diastereoisomeric mixture
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Cytotoxicity against human MT2 cells after 4 days by XTT assay
Cytotoxicity against human MT2 cells after 4 days by XTT assay
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[PMID: 22524483] |
| MT2 | IC50 |
4.2 μM
Compound: 9, NBD-10007, diastereoisomeric mixture
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Inhibition of X4-tropic HIV1 3B gp120-mediated entry into human MT2 cells assessed as Inhibition of p24 production incubated overnight followed by compound wash-out measured after 4 days post-infection by multi-cycle neutralization assay
Inhibition of X4-tropic HIV1 3B gp120-mediated entry into human MT2 cells assessed as Inhibition of p24 production incubated overnight followed by compound wash-out measured after 4 days post-infection by multi-cycle neutralization assay
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[PMID: 22524483] |
Chemical Information
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No. CAS 1375736-65-4
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Peso molecular 436.96
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Fòrmula C20H25ClN4O3S
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SMILES
O=C(C(NC(C1NCCCC1)C2=NC(C)=C(CCO)S2)=O)NC3=CC=C(C=C3)Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NBD-10007 Related Classifications
HY-123756 Related Classifications
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