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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
ABCA4
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "ABCA4" in MCE Product Catalog:
3
3 Cited Publications
Referencia número: HY-W004500
No. CAS: 116-31-4
Category:
Human Gut Microbiota Metabolites Microorganisms Terpenoids Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields
Target:
Referencia número: HY-RS00042
Target:
Áreas de investigación:
ABCA4 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-175664
Target:
Áreas de investigación:
EYE-003 is an orally active RPE65 inhibitor with an IC50 of 102 nM. EYE-003 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-003 suppresses scotopic ERG b-wave amplitude and exerts protective effects against retinal degeneration in Abca4 ⁻/⁻ Rdh8 ⁻/⁻ mice (a STGD1 model) by reducing retinal autofluorescent puncta and preserving outer nuclear layer (ONL) thickness in a dose-dependent manner. EYE-003 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
Referencia número: HY-W004500R
No. CAS: 116-31-4
Referencia número: HY-183032
No. CAS: 3093661-22-1
Áreas de investigación:
ABC transporter modulator-1 (Compound I-5) is an ABC transporter expression enhancer. ABCC6 modulator-1 upregulates the expression of wild-type ABCC6, wild-type ABCB4, and ABCA4 P1380L mutant, with an EC50 of <1 μM for all .
Referencia número: HY-183033
No. CAS: 3093663-15-8
Áreas de investigación:
ABC transporter modulator-2 (Compound I-200) is a ABC transporter expression modulator. ABC transporter modulator-2 upregulates the expression of wild-type ABCC6 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCB4 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCD2 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of the ABCA4 P1380L mutant with an EC50 of <1 μM. ABC transporter modulator-2 can be used in the research of diseases associated with ABC transporter dysfunction .
Referencia número: HY-183035
No. CAS: 3089179-10-9
Áreas de investigación:
ABC transporter modulator-4 (I-677-Isomer 1 (S configuration)) is a ABC transporter expression modulator. ABC transporter modulator-4 is used in studies of ABC transporter dysfunction .
Referencia número: HY-183034
No. CAS: 3093661-88-9
Áreas de investigación:
ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC50 < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction .
Referencia número: HY-183036
No. CAS: 3089179-09-6
Áreas de investigación:
ABC transporter modulator-5 (I-677-Isomer 2 (R configuration)) is a ABC modulator. ABC transporter modulator-5 is used in studies of ABC dysfunction .
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