3093663-15-8
Chemical Structure
ABC transporter modulator-2
- CAS No.: 3093663-15-8
- Formula:C19H15F3N6O3S
- Molecular Weight:464.42
InChIKey: XZBCGLMMHJPIFU-UHFFFAOYSA-N
SMILES: N#CC1=CC(C2=CC=C(NS(=O)(C)=O)C(OC3=C(C)N=C(C(F)(F)F)N=C3C)=N2)=CN=C1
Biological Activity: ABC transporter modulator-2 (Compound I-200) is a ABC transporter expression modulator. ABC transporter modulator-2 upregulates the expression of wild-type ABCC6 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCB4 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCD2 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of the ABCA4P1380L mutant with an EC50 of <1 μM. ABC transporter modulator-2 can be used in the research of diseases associated with ABC transporter dysfunction[1].
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ABC transporter modulator-2 | 96.89% | ABC transporter modulator-2 (Compound I-200) is a ABC transporter expression modulator. ABC transporter modulator-2 upregulates the expression of wild-type ABCC6 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCB4 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCD2 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of the ABCA4P1380L mutant with an EC50 of <1 μM. ABC transporter modulator-2 can be used in the research of diseases associated with ABC transporter dysfunction. | ||||||||||||||||||||
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Keywords
