TLR8 agonist 4
TLR8 agonist 4 showed effective inhibition on wild-type and drug-resistant (lamivudine and entecavir) HBV strains. The IC50 values are 0.15 and 0.10 respectively μM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2761697-69-0
- Fòrmula: C28H27N5O5S
- Peso molecular:545.61
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
|
HBV 0.10 μM (IC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
>10 μM
Compound: 5l
|
Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay
Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay
|
[PMID: 35123297] |
| HepG2 2.2.15 | IC50 |
0.15 μM
Compound: 5l
|
Antiviral activity against Hepatitis B virus infected in human HepG2 2.2.15 cells assessed as inhibition of DNA replication
Antiviral activity against Hepatitis B virus infected in human HepG2 2.2.15 cells assessed as inhibition of DNA replication
|
[PMID: 35123297] |
Chemical Information
-
No. CAS 2761697-69-0
-
Peso molecular 545.61
-
Fòrmula C28H27N5O5S
-
SMILES
COC1=C(C=CC=C1)CSC2=NC3=CC=C(C=C3C(N2CC4=CC=CO4)=O)OCCCOC5=NC(N)=NC=C5
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR8 agonist 4 Related Classifications
HY-144215 Related Classifications
Powered by Bioz