2761697-69-0
2761697-69-0
Chemical Structure
TLR8 agonist 4
- CAS No.: 2761697-69-0
- Formula:C28H27N5O5S
- Molecular Weight:545.61
IUPAC Name: 6-(3-((2-aminopyrimidin-4-yl)oxy)propoxy)-3-(furan-2-ylmethyl)-2-((2-methoxybenzyl)thio)quinazolin-4(3H)-one
InChIKey: JOPGVUPFRGTVIQ-UHFFFAOYSA-N
SMILES: COC1=C(C=CC=C1)CSC2=NC3=CC=C(C=C3C(N2CC4=CC=CO4)=O)OCCCOC5=NC(N)=NC=C5
Biological Activity: TLR8 agonist 4 showed effective inhibition on wild-type and drug-resistant (lamivudine and entecavir) HBV strains. The IC50 values are 0.15 and 0.10 respectively μM.
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TLR8 agonist 4 | TLR8 agonist 4 showed effective inhibition on wild-type and drug-resistant (lamivudine and entecavir) HBV strains. The IC50 values are 0.15 and 0.10 respectively μM. | |||||||||||||||||||||
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