EZH1 - enhancer of zeste 1 polycomb repressive complex 2 subunit Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100518394

About EZH1

Primary_assembly 12: 20,115,297-20,141,749 forward strand.Sscrofa11.1:CM000823.5

This gene has 3 transcripts (splice variants), 234 orthologues and 21 paralogues. Ubiquitous expression in subcutaneous adipose (RPKM 23.3), lung (RPKM 21.5) and 8 other tissues.

EZH1 Products (2)

mRNA Protein Name
NM_001243206.1 NP_001230135.1 histone-lysine N-methyltransferase EZH1
NM_001243206.1 NP_001230135.1 histone-lysine N-methyltransferase EZH1

EZH1 Protein Structure

EZH2_WD-Binding

EZH2_WD-Binding: pfam11616 (38 - 67)

PRC2_HTH_1

PRC2_HTH_1: pfam18118 (158 - 261)

SANT

SANT: cd00167 (432 - 473)

preSET_CXC

preSET_CXC: pfam18264 (563 - 594)

SET_EZH1

SET_EZH1: cd19217 (611 - 746)

  • 0
  • 200
  • 400
  • 600
  • 751 a.a.
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase EZH1

  • enhancer of zeste homolog 1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109108 Valemetostat Inhibitor 99.84% Unkown
HY-109108A Valemetostat tosylate Inhibitor 99.84% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145602 Tulmimetostat Inhibitor 99.79% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15646 UNC1999 Inhibitor 99.87% Unkown
HY-141877 MS4322 Degrader 99.14% Unkown
HY-141877B MS4322 (isomer) 99.87% Unkown
HY-144881 (S)-HH2853 Inhibitor / Unkown
HY-181327 PROTAC EZH2 Degrader-26 Degrader / Unkown
HY-180553 NSD2-IN-6 Inhibitor / Unkown
HY-181308 PROTAC EZH2 Degrader-13 Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens EZH1 NCBI NCBI:2145