(S)-HH2853
(S)-HH2853 (compound 200), a PYRIDINO five membered aromatic ring compound, is a potent EZH1/2 dual inhibitor with an IC50 of <100 nM for EZH2_Y641F. (S)-HH2853 has the potential to be used in the research of anti-tumor or autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 2202678-05-3
- Formula: C31H36F3N7O3
- Molecular Weight:611.66
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
More
Biological Activity
|
EZH1 |
EZH2 Y641N <100 nM (IC50) |
Chemical Information
-
CAS No. 2202678-05-3
-
Molecular Weight 611.66
-
Formula C31H36F3N7O3
-
SMILES
C[C@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)