PIKFYVE - phosphoinositide kinase, FYVE-type zinc finger containing Gene
Species: Macaca fascicularis
Gene Type: protein coding
Gene ID: 102116640
About PIKFYVE
Primary_assembly 12: 96,046,573-96,138,947 forward strand.Macaca_fascicularis_6.0:CM021950.1
This gene has 10 transcripts (splice variants), 205 orthologues and 17 paralogues.
PIKFYVE Products (19)
| mRNA | Protein | Name |
|---|---|---|
| XM_005574104.3 | XP_005574161.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 |
| XM_005574106.3 | XP_005574163.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X3 |
| XM_015432679.2 | XP_015288165.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X11 |
| XM_045367611.1 | XP_045223546.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X14 |
| XM_005574107.3 | XP_005574164.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X4 |
| XM_005574114.3 | XP_005574171.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X12 |
| XM_005574118.2 | XP_005574175.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X15 |
| XM_005574115.3 | XP_005574172.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X13 |
| XM_005574110.3 | XP_005574167.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X8 |
| XM_005574111.3 | XP_005574168.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X9 |
| XM_005574103.3 | XP_005574160.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 |
| XM_005574112.3 | XP_005574169.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X10 |
| XM_005574105.3 | XP_005574162.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X2 |
| XM_015432680.2 | XP_015288166.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X12 |
| XM_005574117.3 | XP_005574174.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X15 |
| XM_005574109.3 | XP_005574166.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X7 |
| XM_045367609.1 | XP_045223544.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X5 |
| XM_005574108.3 | XP_005574165.2 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X4 |
| XM_045367610.1 | XP_045223545.1 | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6 |
PIKFYVE Protein Structure
DEP_PIKfyve
DEP_PIKfyve: cd04448 (259 - 340)
- 0
- 100
- 200
- 300
- 400
- 451 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
1-phosphatidylinositol 3-phosphate 5-kinase |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-14644 | Apilimod | Inhibitor | 99.80% | Phase 2 |
| HY-14644A | Apilimod mesylate | Inhibitor | 99.58% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(18)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-118630 | Vacuolin-1 | Inhibitor | 98.54% | Unkown |
| HY-13228 | YM-201636 | Inhibitor | 98.07% | Unkown |
| HY-15982 | APY0201 | Inhibitor | 99.42% | Unkown |
| HY-119624 | MOMIPP | Inhibitor | 99.00% | Unkown |
| HY-155994 | PIK5-12d | Degrader | 99.15% | Unkown |
| HY-151473 | PIKfyve-IN-1 | Inhibitor | 99.64% | Unkown |
| HY-160477 | DC-SX029 | Inhibitor | 98.07% | Unkown |
| HY-153119 | TMX-4153 | Degrader | 98.96% | Unkown |
| HY-161619 | RMC-113 | Inhibitor | 99.54% | Unkown |
| HY-159625 | WX8 | Inhibitor | 99.43% | Unkown |
| HY-154956 | PIKfyve-IN-2 | Inhibitor | 98.0% | Unkown |
| HY-163943 | UNI418 | Inhibitor | 99.61% | Unkown |
| HY-163133 | PIKfyve-IN-3 | 99.55% | Unkown | |
| HY-170909 | PIKfyve-IN-4 | Inhibitor | 99.53% | Unkown |
| HY-123876 | AS2677131 | Inhibitor | / | Unkown |
| HY-177432 | TMX-4140 | Inhibitor | / | Unkown |
| HY-177091 | AS2795440 | Inhibitor | / | Unkown |
| HY-175631 | PIKfyve ligand-1 | Degrader | / | Unkown |
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