C1D - C1D nuclear receptor corepressor Gene

Homo sapiens

Also known as LRP1; hC1D; Rrp47; SUNCOR; SUN-CoR

Gene ID: 10438 | Gene type: protein coding

About C1D

Cytogenetic location: 2p14 Genomic coordinates (GRCh38): 2:68,041,130-68,063,004 (from NCBI)

This gene has 7 transcripts (splice variants) and 225 orthologues. Ubiquitous expression in bone marrow (RPKM 17.9), adrenal (RPKM 15.5) and 25 other tissues.

Summary

The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the Thyroid Hormone Receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.[provided by RefSeq, Jun 2010]

C1D Products(4)

mRNA	Protein	Name
NM_001190263.2	NP_001177192.1	nuclear nucleic acid-binding protein C1D
NM_001190265.2	NP_001177194.1	nuclear nucleic acid-binding protein C1D
NM_006333.4	NP_006324.1	nuclear nucleic acid-binding protein C1D
NM_173177.3	NP_775269.1	nuclear nucleic acid-binding protein C1D

C1D Protein Structure

Sas10_Utp3

0
100
141 a.a.

Protein Preferred Names

Protein Names

nuclear nucleic acid-binding protein C1D

C1D DNA-binding protein

Recombinant C1D Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74377	C1D Protein, Human (His)	Q13901 (M1-S141)	≥95%

Related Diseases

Diseases

Alias

Inflammatory Bowel Disease 12

IBD12

Pontocerebellar Hypoplasia

Pch	Congenital Pontocerebellar Hypoplasia
Opch	Hypoplasia, Pontocerebellar
Pontoneocerebellar Hypoplasia	Nonsyndromic Pontocerebellar Hypoplasia

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Purity	Rare Diseases
HY-N7092S2	D-Fructose-13C-1	≥98.0%	Unkown
HY-111095S2	D-(-)-Lactic acid-13C-1	/	Unkown
HY-13966S4	2-Deoxy-D-glucose-13C-1	/	Unkown
HY-42680S1	D-Tagatose-13C-1	/	Unkown
HY-B0389S11	D-Glucose-13C-1	/	Unkown
HY-B0400S2	D-Sorbitol-13C-1	/	Unkown
HY-RS01706	C1D Human Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	C1D	VGNC	VGNC:38573
Felis catus	C1D	VGNC	VGNC:80037
Mus musculus	C1D	MGD	MGI:1927354
Bos taurus	C1D	VGNC	VGNC:26614
Rattus norvegicus	C1D	RGD	RGD:1560600
Others	C1D	NCBI

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