LRG1 - leucine rich alpha-2-glycoprotein 1 Gene

Homo sapiens

Also known as LRG; HMFT1766

Gene ID: 116844 | Gene type: protein coding

About LRG1

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,536,402-4,540,036 (from NCBI)

This gene has 2 transcripts (splice variants), 289 orthologues and 22 paralogues. Biased expression in liver (RPKM 150.7), esophagus (RPKM 16.6) and 4 other tissues.

Summary

The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).[supplied by OMIM, Mar 2008]

LRG1 Products(1)

mRNA	Protein	Name
NM_052972.3	NP_443204.1	leucine-rich alpha-2-glycoprotein precursor

LRG1 Protein Structure

LRR_1

LRR_8

LRR_1

LRR_8

0
100
200
300
347 a.a.

Protein Preferred Names

Protein Names

leucine-rich alpha-2-glycoprotein

1300008B03Rik

Recombinant LRG1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70166	LRG1 Protein, Human (HEK293, His)	AAH34389.1 (V36-Q347)	≥95%
HY-P70175	LRG1 Protein, Human (HEK293, Fc-His)	AAH70198.1 (V36-Q347)	≥95%

Related Diseases

Diseases

Alias

Appendicitis

Acute Appendicitis	Acute Appendicitis With Generalized Peritonitis
Acute Appendicitis Nos	Acute Appendicitis With Peritoneal Abscess
Appendiceal Inflammation	Appendicitis, Unqualified
Acute Appendix Inflammation	Acute Appendicitis With Diffuse Peritonitis Following Rupture Or Perforation
Acute Appendicitis With Free Peritonitis	Acute Appendicitis With Free Perforation To The Abdominal Cavity
Perforated Appendix With Generalised Peritonitis	Appendicitis With Perforation And Free Pus In The Peritoneal Cavity
Perforated Appendix With Localised Peritonitis	Acute Appendicitis With Contained Perforation To A Localised Abscess
Acute Appendicitis With Localised Peritonitis With Rupture Or Perforation	Acute Appendicitis With Localised Peritonitis Without Rupture Or Perforation
Acute Appendicitis With Perforation And Contained Peritonitis Into An Abscess	Appendicitis With Abscess
Appendicitis With Peritoneal Abscess	Ruptured Appendix Nos
Acute Appendicitis With No Perforation Or Abscess And No Visible Pus	Acute Appendicitis With No Specification If Perforated Or Not
Acute Appendicitis With Phlegmone

Cecal Disease

Cecal Diseases

Disorder Of Cecum

Communicating Hydrocephalus

Acquired Communicating Hydrocephalus

Hydrocephalus

Hydrocephalus, Nonsyndromic, Autosomal Recessive	Hydrocephalus, X-Linked
Hydrocephalus Adverse Event	Hydrocephaly Nos

Normal Pressure Hydrocephalus

Low Pressure Hydrocephalus	Hydrocephalus Normal Pressure
Hydrocephalus, Normal Pressure	Normal Pressure Hydrocephalus Nos
Nph - [Normal Pressure Hydrocephalus]	Normal Pressure Hydrocephaly

Cardiomyopathy, Dilated, 1e

Left Ventricular Noncompaction 9	Left Ventricular Noncompaction 5
Dilated Cardiomyopathy 1e	Dilated Cardiomyopathy 1s
CMD1E	Cdcd2
Cardiomyopathy, Dilated, 1y	CMD1Y
Cardiomyopathy, Dilated, 1s	CMD1S
Dilated Cardiomyopathy 1y	Dilated Cardiomyopathy With Conduction Defect 2
Dilated Cardiomyopathy With Conduction Disorder And Arrhythmia	Cardiomyopathy, Dilated, With Conduction Disorder And Arrhythmia
Cardiomyopathy, Dilated, With Conduction Defect 2	Cardiomyopathy Dilated With Conduction Defect Type 2
Cardiomyopathy, Dilated 1e	Cardiomyopathy, Dilated 1s
Cardiomyopathy, Dilated 1y	Left Ventricular Non-Compaction 5
LVNC5	Left Ventricular Non-Compaction 9
LVNC9	Cardiomyopathy, Dilated, Type 1e
Cardiomyopathy, Dilated, Type 1s	Cardiomyopathy, Dilated, Type 1y

Cardiomyopathy, Familial Hypertrophic, 1

Asymmetric Septal Hypertrophy	Familial Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy 1	CMH1
Hypertrophic Cardiomyopathy 19	CMH
Ventricular Hypertrophy, Hereditary	Ash
Hypertrophic Subaortic Stenosis, Idiopathic	Cardiomyopathy, Familial Hypertrophic
Cardiomyopathy, Hypertrophic, 1, Digenic	Cardiomyopathy, Familial Hypertrophic 1
Hcm	Hereditary Ventricular Hypertrophy
Idiopathic Hypertrophic Subaortic Stenosis	Hypertrophic Cardiomyopathy
Cardiomyopathy, Hypertrophic, Familial	Cardiomyopathy, Hypertrophic, 1
Familial Asymmetric Septal Hypertrophy	Heritable Hypertrophic Cardiomyopathy
Fhc	Cardiomyopathy, Hypertrophic, Familial, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07784	LRG1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LRG1	RGD	RGD:1359464
Macaca mulatta	LRG1	VGNC	VGNC:74394
Bos taurus	LRG1	VGNC	VGNC:30980
Felis catus	LRG1	VGNC	VGNC:102630
Canis familiaris	LRG1	VGNC	VGNC:42765
Mus musculus	LRG1	MGD	MGI:1924155
Macaca fascicularis	LRG1	NCBI
Others	LRG1	NCBI